Biography

Work in progress

Research Activity

His research activity is directed towards the following issues:

• clinical application of radiofrequency technology (RFID);
• validation of methods and technics for measurements bacteria in liquid media;
• application of low frequency mechanical vibrations to the bone growth and fractures consolidation.

Selected Publications

• Bhattacharya K, Sacchetti C, Costa PM, Sommertune J, Brandner BD, Magrini A, Rosato N, Bottini N, Bottini M, Fadeel B.: Nitric Oxide Dependent Degradation of Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes: Implications for Intra-Articular Delivery. Adv Healthc Mater. 2018 Mar;7(6):e1700916. doi: 10.1002/adhm.201700916. Epub 2018 Jan 15.
• Ceccarelli A, Di Venere A, Nicolai E, De Luca A, Rosato N, Gratton E, Mei G, Caccuri AM.: New insight into the interaction of TRAF2 C-terminal domain with lipid raft microdomains. Biochim Biophys Acta. 2017 Sep;1862(9):813-822. doi: 10.1016/j.bbalip.2017.05.003. Epub 2017 May 9.
• Lazzaro A, Corona A, Iezzi L, Quaresima S, Armisi L, Piccolo I, Medaglia CM, Sbrenni S, Sileri P, Rosato N, Gaspari AL, Di Lorenzo N.: Radiofrequency-Based Identification Medical Device: An Evaluable Solution for Surgical Sponge Retrieval? Surg Innov. 2017 Jun;24(3):268-275. doi: 10.1177/1553350617690608. Epub 2017 Feb 8.
• Bottini M, Magrini A, Fadeel B, Rosato N.: Tackling chondrocyte hypertrophy with multifunctional nanoparticles. Gene Ther. 2016 Jul;23(7):560-4. doi: 10.1038/gt.2016.33. Epub 2016 Apr 14. No abstract available.
• Palumbo C, De Luca A, Rosato N, Forgione M, Rotili D, Caccuri AM: c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition.  J Transl Med. 2016 Feb 4;14:37. doi: 10.1186/s12967-016-0796-x.
• Bottini M, Bhattacharya K, Fadeel B, Magrini A, Bottini N, Rosato N.: Nanodrugs to target articular cartilage: An emerging platform for osteoarthritis therapy.  Nanomedicine. 2016 Feb;12(2):255-68. doi: 10.1016/j.nano.2015.09.013. Epub 2015 Dec 18. Review.
• Ceccarelli A, Di Venere A, Nicolai E, De Luca A, Minicozzi V, Rosato N, Caccuri AM, Mei G.: TNFR-Associated Factor-2 (TRAF2): Not Only a Trimer. Biochemistry. 2015 Oct 13;54(40):6153-61. doi: 10.1021/acs.biochem.5b00674. Epub 2015 Sep 30.
• Bobone S, Miele E, Cerroni B, Roversi D, Bocedi A, Nicolai E, Di Venere A, Placidi E, Ricci G, Rosato N, Stella L.: Liposome-Templated Hydrogel Nanoparticles as Vehicles for Enzyme-Based Therapies. Langmuir. 2015 Jul 14;31(27):7572-80. doi: 10.1021/acs.langmuir.5b01442. Epub 2015 Jul 2.
• Farrotti A, Bocchinfuso G, Palleschi A, Rosato N, Salnikov ES, Voievoda N, Bechinger B, Stella L.:  Molecular dynamics methods to predict peptide locations in membranes: LAH4 as a stringent test case. Biochim Biophys Acta. 2015 Feb;1848(2):581-92. doi: 10.1016/j.bbamem.2014.11.002. Epub 2014 Nov 13.
• Sacchetti C, Liu-Bryan R, Magrini A, Rosato N, Bottini N, Bottini M.: Polyethylene-glycol-modified single-walled carbon nanotubes for intra-articular delivery to chondrocytes. ACS Nano. 2014 Dec 23;8(12):12280-91. doi: 10.1021/nn504537b. Epub 2014 Nov 26.
• Nicolai E, Garau S, Favalli C, D’Agostini C, Gratton E, Motolese G, Rosato N.: Evaluation of BiesseBioscreen as a new methodology for bacteriuria screening. New Microbiol. 2014 Oct;37(4):495-501. Epub 2014 Oct 1.
• Bottini M, Sacchetti C, Pietroiusti A, Bellucci S, Magrini A, Rosato N, Bottini N.: Targeted nanodrugs for cancer therapy: prospects and challenges. J Nanosci Nanotechnol. 2014 Jan;14(1):98-114. Review.
• De Luca A, Mei G, Rosato N, Nicolai E, Federici L, Palumbo C, Pastore A, Serra M, Caccuri AM.: The fine-tuning of TRAF2-GSTP1-1 interaction: effect of ligand binding and in situ detection of the complex. Cell Death Dis. 2014 Jan 23;5:e1015. doi: 10.1038/cddis.2013.529.
• Sacchetti C, Rapini N, Magrini A, Cirelli E, Bellucci S, Mattei M, Rosato N, Bottini N, Bottini M.: In vivo targeting of intratumor regulatory T cells using PEG-modified single-walled carbon nanotubes.
• Sacchetti C, Motamedchaboki K, Magrini A, Palmieri G, Mattei M, Bernardini S, Rosato N, Bottini N, Bottini M.: Surface polyethylene glycol conformation influences the protein corona of polyethylene glycol-modified single-walled carbon nanotubes: potential implications on biological performance. ACS Nano. 2013 Mar 26;7(3):1974-89. doi: 10.1021/nn400409h. Epub 2013 Feb 28.
• Zahorodny W., Shenouda J., Howell S., Rosato N., Peng B., Mehta U.: Increasing autism prevalence in metropolitan New Jersey. Autism. 2014 Feb;18(2):117-26. doi: 10.1177/1362361312463977. Epub 2012 Nov 30.

Teaching – link to Didattica web