Biography

Work in progress

Research Activity

1) Laboratory development and managing.
2) Molecular biology techniques
3) Microbiology techniques.
4) Immunobiosensors for analisys of enviromental pollution and food contaminants.
5) Cellular immunology
6) Immunochemistry
7) Cell culture and monoclonal antibody production
8) Drug design and HTS
9) Activity evaluation of new drugs against parasites.

Selected Publications

[1]. Ciaccio C, Coletta A, De Sanctis G, Marini S., Coletta M. (2008) Cooperativity and allostery in haemoglobin function. IUBMB Life. Feb;60(2):112-23

[2]. Gemma S, Campiani G, Butini S, Kukreja G, Coccone SS, Joshi BP, Persico M, Nacci V, Fiorini I, Novellino E, Fattorusso E, Taglialatela-Scafati O, Savini L, Taramelli D, Basilico N, Parapini S, Morace G, Yardley V, Croft S, Coletta M, Marini S, Fattorusso C. (2008) Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies. J Med Chem. 2008 Mar 13;51(5):1278-94. Epub 2008 Feb 16.

[3]. Monaco S, Gioia M, Rodriguez J, Fasciglione GF, Di Pierro D, Lupidi G, Krippahl L, Marini S, Coletta M. (2007) Modulation of the proteolytic activity of matrix metalloproteinase-2 (gelatinase A) on fibrinogen. Biochem J. Mar 15;402(3):503-13.

[4]. Saladino R, Fiani C, Crestini C, Argyropoulos DS, Marini S, Coletta M. (2007) An efficient and stereoselective dearylation of asarinin and sesamin tetrahydrofurofuran lignans to acuminatolide by methyltrioxorhenium/H(2)O(2) and UHP systems. J Nat Prod. Jan;70(1):39-42.

[5]. Gioia M, Monaco S, Fasciglione GF, Coletti A, Modesti A, Marini S, Coletta M. (2007) Characterization of the Mechanisms by which Gelatinase A, Neutrophil Collagenase, and Membrane-Type Metalloproteinase MMP-14 Recognize Collagen I and Enzymatically Process the Two alpha-Chains. J Mol Biol. May 11;368(4):1101-1113. Epub 2007 Mar 2.

Teaching – link to Didattica web

Work in progress